Posted by bleauberry on March 3, 2013, at 11:46:24
In reply to SLS- Anyone? Effexor most like Tramadol?, posted by Sheilac on March 1, 2013, at 7:49:30
Effexor is the closest to Tramadol. They are not however the same. Similar.
No one knows exactly how any of our meds work. But basically, tramadol is hitting serotonin primarily, norepinephrine secondarily, and the opioids to a lesser degree, but it is somehow the complicated maze connecting them all that makes tramadol what it is.
Effexor is 30 parts serotonin to 1 part norepinephrine. It also has some other unknown indirect link to the opioid system, and there are theories that is why the withdrawals are so harsh.
poster:bleauberry
thread:1039150
URL: http://www.dr-bob.org/babble/20130222/msgs/1039432.html