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Re: A nice surprise, Dr. Gillman responds to question » caller

Posted by SLS on January 5, 2013, at 8:56:04

In reply to Re: A nice surprise, Dr. Gillman responds to question, posted by caller on January 4, 2013, at 14:46:20

You have a good handle on pharmacology.

> > Buspar (buspirone) might help, but it often takes a few weeks to begin working.
>
> Ah, precisely the kind of information I was looking for!
> Do you think 5 mg BID of buspirone should be safe with 50 - 60 mg Parnate?

1-PP? Yeah, it works in a manner similar to Remeron. I am hesitant to suggest that the combination is perfectly safe. I haven't tried it myself. Hypertension is the major concern. 1-PP is the reason I have avoided Buspar. Remeron and an investigational drug called idazoxan both exacerbate my depression. I think the culprit mechanism is NE alpha-2 antagonism.

I wish I could be of more help. Perhaps someone who has actually tried combining a MAOI with Buspar will offer some feedback.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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