Re: Bifidobacteria reduce depression

Posted by SLS on December 29, 2012, at 12:18:42

In reply to Re: Bifidobacteria reduce depression » Trotter, posted by rca on December 29, 2012, at 11:25:12

Fascinating stuff. I feel so wonderfully dumb.

- Scott

> > >since endotoxin has a strong affinity for the saturated fat transport system through the gut wall and into the blood stream (Deopurkar et al., 2010, below).
> > >
> >
> > Can you please provide evidence to support your statement that the translocation of endotoxin is facilitated by a "saturated fat transport system"? It is my current understanding that a high fat diet increases endotoxemia by affecting the bowel bacterial composition, specifically by reducing bifidobacteria. I think it is the bifidobacteria which help maintain intestinal integrity.
>
> Yes. Animal fat may play a profound role in the pathogenesis of after-meal inflammation by increasing the absorption of the endotoxins, since endotoxin has a strong affinity for the saturated fat transport system (chylomicrons lipoproteins that transport dietary long chain saturated fatty acids through the gut wall and into the blood stream). So animal fat may play a role in boosting endotoxin absorption, but the primary reason all those studies show increased inflammation from animal foods, but not from unfermented plant foods, may be the load of dead bacteria, which release endotoxins that are absorbed into our system leading to the endotoxemic inflammation we see after meat, egg, and dairy consumption.
>
> The transport system is nicely explained here: http://www.google.com/url?sa=t&rct=j&q=&esrc=s&frm=1&source=web&cd=1&ved=0CDQQFjAA&url=http%3A%2F%2Fwww.jlr.org%2Fcontent%2Fearly%2F2008%2F10%2F28%2Fjlr.E800018-JLR200.full.pdf&ei=oSTfUISRLufg2wXLjIHoBQ&usg=AFQjCNEiN37xnCExm09raRc1iapzMaLxZQ&sig2=qh8SmOEKpm3S84kDmqMW_A
>
> http://www.ncbi.nlm.nih.gov/pubmed/22210577
>

Some see things as they are and ask why.
I dream of things that never were and ask why not.
- George Bernard Shaw

Thread

High fat diet -) inflammation -) depression Trotter 12/19/12
...
Re: High fat diet -) inflammation -) depression » larryhoover rca 12/28/12
Re: High fat diet -) inflammation -) depression » Trotter rca 12/28/12
Re: Bifidobacteria reduce depression » rca larryhoover 12/28/12
Re: High fat diet -) inflammation -) depression Trotter 12/28/12
Re: Bifidobacteria reduce depression Trotter 12/28/12
Re: Bifidobacteria reduce depression Trotter 12/28/12
Re: High fat diet -) inflammation -) depression » Trotter SLS 12/28/12
Re: High fat diet -) inflammation -) depression Trotter 12/28/12
Re: High fat diet -) inflammation -) depression » Trotter SLS 12/28/12
Re: High fat diet -) inflammation -) depression » Trotter SLS 12/28/12
Re: Bifidobacteria reduce depression » larryhoover rca 12/29/12
Re: Bifidobacteria reduce depression » Trotter rca 12/29/12
Re: Bifidobacteria reduce depression SLS 12/29/12
Re: Bifidobacteria reduce depression » rca Trotter 12/29/12
Re: Bifidobacteria reduce depression » rca Trotter 12/29/12
Re: Bifidobacteria reduce depression » Trotter rca 12/30/12
Re: Bifidobacteria reduce depression Trotter 12/30/12
Re: Bifidobacteria reduce depression Trotter 12/30/12
Re: Bifidobacteria reduce depression SLS 12/31/12
Re: Bifidobacteria reduce depression » SLS Trotter 12/31/12
Link between endotoxemia and MDD Trotter 12/31/12
Re: High fat diet -) inflammation -) depression » Trotter SLS 1/3/13
Re: Bifidobacteria reduce depression » Trotter Rosscoe 4/1/15
Re: Bifidobacteria reduce depression (nm) » Trotter Rosscoe 4/1/15

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