Posted by MrAnderson on December 22, 2012, at 23:40:12
In reply to Re: High dose lamictal » MrAnderson, posted by alchemy on December 20, 2012, at 22:12:27
> > I'm taking 650 mg of Lamictal right now for depression so you can definitely go higher. You should definitely try magnesium (citrate, taurine). When I started on the magnesium I was able to stop taking the Parnate I was on, I think it affects glutamate transmission to some extent like Lamictal does.
> >
> > There are other things to try (Riluzole, N-Acetyl-Cysteine) that work somewhat similar to Lamictal. I don't have much experience with those so I can't say for sure.
>
> I have been on 400mg of lamictal for probably a couple years now. I havent noticed any help for my depression, but i think it has helped with my agitation (although it initially made it worse). What made u increase ur dose to that level? Did u find milder anti-dep effects at a lower dose?
>
>I was on 300 mg for several years, reduced it to 100 mg for another couple years. I did see an antidepressant effect around 300 mg. But earlier this year I was making a lot of changes with my meds and the Lamictal started pooping out, so I've been raising it every week or two since it keeps pooping out now.
I think that if people don't see a difference at 400-500 mg then going above that for bipolar/depression probably won't make too much of a difference. The only reason that I keep raising it is that it initially worked at a lower dose but stopped working.
poster:MrAnderson
thread:1033350
URL: http://www.dr-bob.org/babble/20121217/msgs/1033607.html