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can a generic help where brand-name didn't?

Posted by g_g_g_unit on December 21, 2012, at 0:20:36

I recently tried brand-name Memantine (Ebixa) for severe, treatment-resistant OCD and experienced a worsening of symptoms with each escalation of dose (from 2.5mg - 15mg).

However, I have come across a member on another board who *swears* by the Sun Pharma-produced generic, claiming to have seen no results with the brand name.

I actually have about two-month's worth of the generic on-hand and another 4 weeks until I potentially see my psychiatrist again. Considering I've all but given up hope in finding any relief from my symptoms, I'd be wondering whether it would be worth experimenting with the generic during that period.

Obviously no one can directly instruct me on what to do, but I was just curious whether there was a general phenomenon of patients potentially responding to a generic whereas they had no (or an adverse) reaction to a brand-name of a specific drug. The overall Memantine experience was rather unpleasant, so it isn't something I would explicitly be want to be replicating if there was no hope I might see different results this time around.

I suppose I could always try a low dose (5mg) for a week and see if the general trend (increased anxiety/agitation) repeats itself.

 

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poster:g_g_g_unit thread:1033425
URL: http://www.dr-bob.org/babble/20121217/msgs/1033425.html