Re: Nardil too much weight gain. -) Marplan? » Lamdage22

Posted by SLS on December 4, 2012, at 6:45:40

In reply to Nardil too much weight gain. -) Marplan?, posted by Lamdage22 on December 4, 2012, at 5:14:34

> Is Marplan weight neutral? I dont want to give up the GABA-T inhibitory effects of Nardil and believe, that Marplan has them, too.
I don't think that Marplan inhibits GABA-transaminase activity (and thus raise GABA levels) in the brain like Nardil does, even though both drugs are hydrazines.
> Now i dont know if Marplan is weight neutral already?
I found that Marplan was relatively weight-neutral when compared to Nardil.
> Or should i switch to Parnate?
What condition or symptoms are you attempting to treat?
I would say that a higher percentage of people respond to Parnate than to Marplan. Parnate is probably less liable than Nardil to precipitate mania, but it certainly can. I found Marplan to be very tolerable with respect to side-effects.
> Also, i have Zyprexa for "Emergency" anti-manic/psychotic.
If you are bipolar, it might be desirable to take some type of anti-manic or mood-stabilizer on a steady basis. It sounds like you are either bipolar I or schizoaffective. Of the neuroleptic antipsychotics, only Geodon and Latuda are truly weight-neutral. I think that Latuda would be safer to add to an MAOI than Geodon because Geodon inhibits the reuptake of serotonin like SSRIs do. I would be concerned that Geodon might precipitate serotonin syndrome, even though the drug is not terribly potent as a reuptake inhibitor. Latuda is currently being looked at for bipolar depression. Among the anticonvulsants, I would look at Trileptal and Depakote as providing protection against mania. Of course, lithium is a valid alternative. Depakote and lithium can, but not always, produce weight gain. I never gained weight with either of these drugs.
Good luck with whatever you choose.

- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.
- George Bernard Shaw

Thread

Nardil too much weight gain. -) Marplan? Lamdage22 12/4/12
Re: Nardil too much weight gain. -) Marplan? » Lamdage22 SLS 12/4/12
Re: Nardil too much weight gain. -) Marplan? jono_in_adelaide 12/4/12
Re: Nardil too much weight gain. -) Marplan? Lamdage22 12/5/12
Due to candida, i refuse all weight gain meds (nm) Lamdage22 12/5/12
Re: Due to candida, i refuse all weight gain meds » Lamdage22 SLS 12/5/12
Re: Due to candida, i refuse all weight gain meds Lamdage22 12/5/12
I also take T3.. (nm) Lamdage22 12/5/12
Re: Nardil too much weight gain. -) Marplan? » Lamdage22 ed_uk2010 12/7/12
Re: Nardil too much weight gain. -) Marplan? » ed_uk2010 SLS 12/7/12
Re: Nardil too much weight gain. -) Marplan? » SLS ed_uk2010 12/8/12
Re: Nardil response Cee 12/8/12
Re: Nardil response » Cee SLS 12/8/12
Will certainly change to Parnate and NO more Zypr. Lamdage22 12/11/12
...
Difficulty telling right from wrong (nm) Lamdage22 12/15/12

Post a new follow-up

Notify the administrators

Start a new thread

poster:SLS thread:1032433
URL: http://www.dr-bob.org/babble/20121130/msgs/1032436.html