Posted by Delna on November 27, 2012, at 2:08:00
In reply to Re: Depression is Infectious Inflammation » Delna, posted by g_g_g_unit on November 27, 2012, at 1:47:14
Hi,
Speaking personally, since we all react differently to drugs, I would try the velnafaxine. The difference here is that you have the noradrenaline boost kicking in at about 150mg so its not numbing in my experience. If u titrate up slow you should not get anxiety. Its actually great for anxiety. I know its one of the most 'hated' drugs due to withdrawal etc but it changed my life. I couldn't leave the house because i kept having to check that my face was not deforming every few minutes, or then checking something else like that my legs still worked. I mean, i was hopping from one foot to the other all night just to make sure! I was terrified all the time. It was awful- am sure you can relate. Now, all my OCD is under control as is anxiety.
Venlafaxine is worth a shot especially if your life is out of control because of the OCD. Mine was. I would have resisted high doses too but my OCD became delusional and i ended up in hospital and with no say! Best thing in retrospect!
Well at least u know there is a potential drug in case you come up against a wall. You have a fall back drug to try.> Thanks and my apologies as well for the late reply .. only just noticed your response.
>
> Yeah, I was trying Parnate for depression/OCD without success; I even retried it recently out of desperation and had a slightly better response (psychiatrist was willing to prescribe a higher dose), but still no benefits as far as anxiety is concerned.
>
> The highest SSRI dose I've tried was 20mg of Lexapro, which I'm aware is still sub-therapeutic for OCD; it didn't do anything for my anxiety. I don't know though.. I felt so numb, apathetic, spacey etc. that the prospect of high doses of SSRIs kind of scares me. I've also tried Prozac and Zoloft, which I couldn't tolerate due to anxiety.
>
> I admit my OCD is out-of-control now though, so maybe venlefaxine would be worth a shot.
>
>
> > > Posting on another board, however, someone strongly suggested I try Augmentin XR or a similar anti-biotic .. apparently their son was totally asymptomatic for strep (which is one cited cause of early-onset OCD) and, after failing to respond to conventional treatment, experienced quite a dramatic remission in symptoms.
> > >
> > > My case is kinda different (OCD onset at 19), but I'm thinking about asking my GP to prescribe an AB ..
> > >
> > Hi,
> > Sorry for the delay in posting back. I remember you too. :) We were trying parnate at roughly the same time. It failed for you too, i think. You were trying it for OCD right?
> > I have severe, childhood onset OCD but I am lucky in that it is suppressed by Ssri type drugs. I have had so much augmentin, it has done nothing positive because unlike kids we aren't still actively infected. We can't be.
> > But is your OCD completely resistant to psychiatric drugs? Are you sure about that? I am asking because of my personal experience with drugs and doses. If the dose is not pushed up high as needed, u see no benefit.
> > When I am off SSRI type drugs and my OCD comes back, I need very high doses to control it. With Venlafaxine I need a very minimum of 375mg (for example)- lower than that and the OCD is still awful. And i need that dose for several months before I am stable. So i am wondering if you have taken a dose high enough for your needs. For me, once the ocd remits, I can lower the dose but I can never stop it though. None of the other drugs I take help with my OCD.
> > I sincerely hope your doctor has tried high enough doses , for long enough before ruling simpler drugs like venlafaxine out, as that would be a real shame. I know OCD is v hard to treat and it is an utter nightmare to live through. It's the aspect of this entire illness that I am genuinely terrified of. But for all you know you may just need a super high dose of one drug to benefit, like I did. I also know doctors are reluctant to push doses up when sometimes that is all it takes to help the patient. The two most effective drugs for OCD for me have been paroxetine and venlafaxine. Neither is lovely but they can work wonders. Especially venlafaxine. I urge you, if you haven't already tried this and are in a bad place, to give a drug like venlafaxine a shot, at high dose.
> > Meanwhile, let me keep u posted on the minocycline adventure. Maybe all of us have inflamed brains!
> > Take Care
> > Divya
> >
>
>
poster:Delna
thread:1030987
URL: http://www.dr-bob.org/babble/20121113/msgs/1031999.html