Posted by SLS on November 17, 2012, at 11:27:37
In reply to Re: Zipra/Sulpr link? Scott? ALERT:mention of *S* word » SLS, posted by Delna on November 17, 2012, at 8:08:39
Hi Delna.
http://www.ncbi.nlm.nih.gov/pubmed/19337725
:-)
- Scott
--------------------------------------------
> > Abilify and Latuda are good choices according to the most current literature. If you feel that you need an energy boost, I would first establish Abilify, Lamictal, and Wellbutrin, and then consider adding minocycline afterwards.
> >
> > Sulpiride might poop out because dopamine D2 presynaptic receptors eventually upregulate and reduce the synthesis and release of dopamine, thus reversing the initial increase in DA release.
> > Yes, Latuda and Sulpiride both exhibit 5-HT7 receptor blockade.
>
> If Abilify doesn't work, then Latuda makes a good second choice.
> >
> > -------------------------------------
> >
> > Effexor: 300 mg/day (Perhaps substitute Cymbalta for pain symptoms)
> >
> > Wellbutrin: 300-450 mg/day
> >
> > Lamictal: 200 mg/day
> >
> > Abilify: 2.0-10.0 mg/day
> >
> > Ritalin: 40 mg/day (Focalin might be better)
> >
> > Klonopin: 2.0 mg/day
> >
> > gabapentin: 900 mg/day
> >
> > -------------------------------------
> >
> >
> > - Scott
>
>
> Hi Scott,
> thanks a lot for your reply!
>
> You said:
> "Yes, Latuda and Sulpiride both exhibit 5-HT7 receptor blockade. "
>
> Did you mean lurasidone and ziprasidone have action at 5HT7? Or Lurasidone & Sulpiride?
> I have not seen anything that talks about sulpiride and 5ht7 so if you've read that somewhere, that maybe the answer ! Because I am sure that Ziprasidone has action at 5HT7 and if sulpiride does as well, thats what links them!! Can you please tell me where you read about sulpiride and 5HT7?
>
> Then latuda would be worth a shot. It may really work!
>
> I tried Abilify. It was really uselss.
>
> My doctor wants me to take 400mg minocycline, then add mementine. That also acts on glutamate. Gabapentin is way too sedating. I could only tolerate it whilst on Geodon, when nothing could r oversedate me.
>
> Thanks again,
> Your input is so helpful!
> D
>
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1031452
URL: http://www.dr-bob.org/babble/20121113/msgs/1031464.html