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Re: Do anticholinergic side-effects go away with time?

Posted by papillon2 on November 2, 2012, at 1:38:50

In reply to Re: Do anticholinergic side-effects go away with time? » enndub, posted by phidippus on October 31, 2012, at 22:51:41

I have taken Nortriptyline. For me (your mileage may vary) some of the anti-chlorinergic side effects went away, others lessened, others stayed the same or worsened over time.

Went away:
- Flu-like symptoms
- Orthostatic hypotension

Lessened:
- Tachycardia
- Chest pain
- Palpitations
NB: these were thanks in part to co-commitant use of fish oil and baby aspirin. All would worsen to previous levels if I missed a couple of doses.

Stayed the same and/or worsened
- Constipation
- Gas and gas pain
- Bloating
- Intolerance to various foods
NB: Movicol and simethicone has helped partly with the first three but they are still a major problem. I've had to reduce my dose and have a referral to see a gastroenterologist.

I found it took about a month for my body to get used to each dose increase and stabilize in terms of side effects.


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URL: http://www.dr-bob.org/babble/20121029/msgs/1030502.html