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Re: Drug Experts help me with something Please! » gilmourr

Posted by phidippus on November 1, 2012, at 18:02:58

In reply to Re: Drug Experts help me with something Please!, posted by gilmourr on November 1, 2012, at 16:44:55

>The 3 that have made me cold are Parnate, Cymbalta and Nardil (All NE based)

Have you eliminated all possibilities?

>Definitely something can, you're saying if I'm hypertensive they wouldn't be able to do anything about that?


I forgot, Clonidine reduces norepenephrine.

Clonidine treats high blood pressure by stimulating α2 receptors in the brain, which decreases cardiac output and peripheral vascular resistance, lowering blood pressure. It has specificity towards the presynaptic α2 receptors in the vasomotor center in the brainstem. This binding decreases presynaptic calcium levels, and inhibits the release of norepinephrine (NE). The net effect is a decrease in sympathetic tone


Eric


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URL: http://www.dr-bob.org/babble/20121029/msgs/1030480.html