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Re: 1st Mood Stabilizer-What Would You Start With? » Raisinb

Posted by SLS on September 18, 2012, at 22:53:12

In reply to Re: 1st Mood Stabilizer-What Would You Start With? » Gia36, posted by Raisinb on September 18, 2012, at 20:11:08

Don't forget to look at Latuda (lurasidone) for bipolar depression. It will probably be approved for this indication eventually. It is an antipsychotic with antidepressant properties. Right now, only Seroquel is approved as monotherapy for the treatment of acute bipolar depression. Symbiax is polytherapy, of course. Lamictal is approved only for maintenance as a mood-stabilizer.

Latuda is a potent 5-HT7 receptor antagonist. This is a property that is thought to convey antidepressant effects. The only other psychotropics that I am aware of that do this are sulpiride and amisulpride - two antipsychotics that are not available in the US.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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