Posted by SLS on August 17, 2012, at 15:21:14
In reply to Re: Starting minocycline. » SLS, posted by brynb on August 17, 2012, at 13:45:02
> Scott-
>
> I find this so interesting. I have an Rx for minocycline from my dermatologist (for breakouts). It's 100mg capsules. I'm thinking of adding it to my current regimen. What's the proper dosage for treating depression/inflammation?
>
> -bMost studies of minocycline to treat psychiatric illness have used 100 - 150 mg/day. I would start at 50 mg once per day for a few days, then 50 mg twice per day thereafter. I really don't have a "feel" for the behavior of this drug in other people yet. However, some people might be too sensitive to starting minocycline at 100 mg/day.
If it turns out that I am currently experiencing the beginnings of an antidepressant response to minocycline, then it is apparent to me that some people will experience an improvement within the first week. I have seen this before with this drug. However, it is important to note that I am taking other psychotropic drugs, including Lamictal and Abilify. Lamictal, in particular, might act in concert with minocycline to disinhibit mesolimbinc dopamine release by reducing glutamate activity in the VTA. The result is increased dopamine activity. I'm sure it's not that simple, though.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1023257
URL: http://www.dr-bob.org/babble/20120803/msgs/1023530.html