Posted by jono_in_adelaide on August 14, 2012, at 1:13:00
In reply to Re: Straterra as possible augment for Nortriptyline?, posted by SLS on August 13, 2012, at 5:21:05
I suggested sertraline because it doesnt block the enzymes that metabolise nortriptyline, and has generaly been shown to be among the best of the SSRI's. Of course, some might be better on citralopram or escitralopram, paroxetine and fluoxetine would seem to be bad ideas, because of their interaction with nortriptyline metabolism.
Effexor could be good - realy, whatever works, do it!
> > A more logicsl potentiator for nortriptyline might be sertaline, starting dose 50mg/day, increasing upto 100mg per day or even 200mg per day if needed (nortriptyline mainly effects noradrenalin, and sertraline mainly effects seretonin, so together they can give the "one-two" knockout punch the depression, anxiety etc
> >
> > Also, get your blood levels of nortriptyline checked to make sure that you're in "the zone"
>
> I found Effexor to be much better as an adjunct to nortriptyline than I found Zoloft. I'm not sure that any one SRI is going to be superior for everyone. The only caveat would be to use less nortriptyline if one chooses Prozac or Paxil as the adjunctive SRI - perhaps using only half the usual dosage. The blood tests would help to determine this.
>
>
> - Scott
poster:jono_in_adelaide
thread:1023133
URL: http://www.dr-bob.org/babble/20120803/msgs/1023247.html