Posted by phidippus on August 3, 2012, at 22:41:11
In reply to Re: NMDA Antagonists + Synthetic Opioids » phidippus, posted by brynb on August 3, 2012, at 7:18:01
Tramadol is a weak mu/kappa agonist. ITss a much more powerful NMDA antagonist and really likes to hit those S/N receptors. You probably did ok with Tramadol's SNRI activity on account of its weak opioid effect.
What I find funny is people going off on Tramadol as being so causing of dependency. They don't realize how weak of an opiate Tramadol is. The idea of getting hooked on it makes me laugh.
Subutex is Bupernorphine with nalexone added. I prefer my Bup straight. Be careful with Subutex...As an opioid agonist its about 50 times stronger than morphine.
Eric
poster:phidippus
thread:1022575
URL: http://www.dr-bob.org/babble/20120803/msgs/1022688.html