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Re: The Serotonin Syndrome Myth And Not Being Listless

Posted by Brainbeard on July 28, 2012, at 17:58:41

In reply to Re: The Serotonin Syndrome Myth And Not Being Listless » Brainbeard, posted by phidippus on July 28, 2012, at 14:17:55


>
> Easy for you to say...I've already suffered seratonin syndrome twice this year-it is not a pleasant thing to go through, all shakes and sweats, increased anxiety, visual disturbances, fever, hallucinations.

Oh boy... I'm afraid I've been overgeneralizing. Maybe my shrink, who IS afraid I'll get SS, is right after all... But I don't get it, your situation would disprove the hypothesis that SS is caused by 5HT2 over-stimulation... Since Latuda antagonizes 5HT2A-receptors. WTF??

>
> Its rare because most people don't push their meds like you or I do!

We are brave.

>
> I found Viibryd to be more effective than Clomipramine. And Clomipramine made me anorgasmic and cognitively bleh.

Unfortunately, we don't have Viibryd here in Holland, neither do we have Latuda. We're always 40 years behind the United States...
>
> Why don't you augment with an antipsychotic? Lower those dopamine levels in your nucleus acumbens (it is found people with OCD have higher levels of ddopamine in the nucleus accumbens-in deep brain stimulation an electrode is attached to the niucleus accumbens to lower symptoms)

I gotta read into deep brain stimulation. My psychiatrist is suggesting I should volunteer for an implant with a professor in Utrecht who is pioneering in this area. So it is in fact anti-dopaminergic? But only in the nucleus accumbens? Boy, I gotta read up.

But hey - I do take an antipsychotic; it's flupentixol, brand name Fluanxol. It's a lesser known AP; it is an oldie but it has a pharmacological profile more akin to the AAP's. So there is some D2-antagonism going on in my brain. But maybe I would need more.

>
> By the way, I'm doing great. my OCD has taken a vacation and I'mm going back to school for psychology, actually neuroscience to be exact. What are you up to?
>

That's great! I'm enjoying my job, mostly... It may be insane, but I really like going to work and hanging out with my colleagues.
I find the family life harder to swallow. Not to speak of my marriage.
I'm trying to start up again creatively and musically, but it's still pretty hard, even with all the feel-good meds I take.

Neuroscience... Interesting enough.

See you around!

-Marten


Current meds: Zoloft (sertraline) 250mg, Neurontin (gabapentin) 1800mg, clomipramine 75mg, Concerta 18mg + methylphenidate (Ritalin) 5mg a time, flupentixol 0,5mg. PRN: alprazolam, clonazepam.


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poster:Brainbeard thread:1021657
URL: http://www.dr-bob.org/babble/20120718/msgs/1022322.html