Posted by phidippus on July 26, 2012, at 22:24:11
In reply to Parnate decision, posted by g_g_g_unit on July 21, 2012, at 8:52:12
MAOIs are reccommended as a last line of treatment according to the APA treatment algorithm for OCD. Parnate is not working for you and its time to give it up.
According to the APA treatment algorithm for OCD, the first line of treatment medicine wise is an SSRI. If you fail to respond to the SSRI or there is only moderate improvement, the APA recommends augmentation with an atypical antipsychotic.
The logic is thus: in patients with OCD it has been shown that there are deficiencies in seratonin in the prefrontal cortex-glutamate levels are also too high. Treatment with an SSRI boosts deficient levels of seratonin and corrects the imbalance. It doesn't stop there though. It has also been shown that folk with OCD have elevated levels of dopamine in the nucleus acumbens. Augmentation with an atypical antipsychotic corrects this imbalance.
I have OCD and am doing great, mostly due to the fact I follow th APA guidelines for the treatment of OCD. My meds are:
Viibryd 60 mg
Lithium 1200 mg
Abilify 10 mg
Klonopin 2 mgTry the formula. Get on an SSRI at a therapeutic level, then augment with an atypical antipsychotic. Parnate is just the wrong choice.
Eric
poster:phidippus
thread:1021887
URL: http://www.dr-bob.org/babble/20120718/msgs/1022192.html