Posted by SLS on June 25, 2012, at 16:44:53
In reply to Re: Adding Parnate and prazosin + Topamax, posted by creepy on June 25, 2012, at 8:30:37
Hi Creepy.
> I rapid cycled on 50mg topamax.. might be a little rough titrating up to 100.
Were you steadily depressed prior to beginning Topamax?
> I was a hyper-responder when I took it though. at 50mg I had some really intense side effects most dont get until higher doses. Maybe something else I was taking at the time raised my levels? Dunno.
What sorts of effects did you experience?
> Its supposedly good at taming angry outbursts in PTSD.
I didn't know that. I have seen it do this for bipolar disorder, mixed-state.
> But whether thats due to calming a mixed state or something else like slowing the amygdala I have no idea.
That's an interesting thought.
> I get the feeling the docs dont either! =(
I know.
> Zoloft has been good on my PTSD, but my body seems to respond by 'somatizing' the depression so now I have pain and fatigue.
Experiencing the somatic symptoms of depression or drug side effects is not the same thing as "somatization".
> What symptoms make your doc think you have PTSD?
Childhood history of physical abuse and neglect.
He thinks that I might have "developmental PTSD", and that this, in part, is driving the depression and creating a biological substrate for my presentation of rapid relapse upon response to antidepressant treatment.
http://www.positivehumandevelopment.com/developmental-ptsd.html
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1005781
URL: http://www.dr-bob.org/babble/20120608/msgs/1020202.html