Posted by SLS on April 29, 2012, at 5:59:34
In reply to Re: feel foggy/stoned on Parnate » SLS, posted by g_g_g_unit on April 28, 2012, at 8:31:48
> I will need to look into the Dexedrine thing more closely.
I am baffled by what Dr. Gillman told you.
I can't find any reason why Dexedrine cannot be combined with Parnate for most people. I have been reading about amphetamines since 1983, and never came across anything that suggests that it releases serotonin or otherwise produces serotonin syndrome when combined with an MAOI. Hypertension is a concern for some people, but this is a catecholamine thing. The thing is, new properties are discovered in old drugs quite frequently, so there there must be literature that I have not seen yet.
Here is an excerpt of what Dr. Gillman writes on the subject:
"Amphetamine and MAOIs have also been in use together for 40 years and there are few deaths from apparent serotonin toxicity reported with amphetamine. Amphetamine has weak serotonergic effects; and there seems little risk of precipitating serotonin toxicity if combined with MAOIs."
One must read the whole article. He apparently contradicts himself. The doctor certainly seems ambivalent.
http://www.psychotropical.com/CNS_stimulants_with_MAOIs.shtml
Medline (Pubmed) is a reasonably comprehensive repository of medical literature. So far, I have not seen anything describing amphetamine in such a way.
I guess it makes sense to accept your doctor's assessment of amphetamine at this point. I would like to see more proof, though.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1016518
URL: http://www.dr-bob.org/babble/20120425/msgs/1016672.html