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Re: i cant even smile. » Alexei

Posted by SLS on April 27, 2012, at 7:05:44

In reply to Re: i cant even smile. » SLS, posted by Alexei on April 26, 2012, at 13:50:32

> Thank you for this. The only concern would be postural hypotension.... since both drugs can cause it.

It helps to hydrate with a fluid that contains electrolytes like Gatorade. For me, the hypotension was worst at the beginning of treatment and mitigated over time. It was well worth the wait.

> Would it be possible to remain on vyvanse?

I don't know about Vyvanse, but I have tried Dexedrine along with Parnate and desipramine. There were no adverse effects.

http://www.dr-bob.org/tips/split/MAOIs-in-high-doses-and-wi.html

"Combined MAOI, TCA, and direct stimulant therapy of treatment-resistant depression"

http://www.ncbi.nlm.nih.gov/pubmed/3997787

I wish I could find the full text.

http://www.dr-bob.org/tips/split/TCAs-+-MAOIs.html

> What would make desipramine the preferred TCA?

I was making reference to using desipramine when weight-gain is a concern. For me, nortriptyline produces a better antidepressant response than desipramine. However, the first time I entered a period of extended remission, it was the result of treatment using a Parnate + desipramine combination.

> I know it is one of the most potent NRI's. Could low dose seroquel be used for insomnia?

I can't think of any reason why not.

http://www.theannals.com/content/40/3/567.full

Interestingly, high dosages of Seroquel result in a certain amount of NE reuptake inhibition via an active metabolite.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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