Posted by Vincent_QC on March 30, 2012, at 16:13:10
In reply to Re: Benzo free med suggestions for early awakening » Vincent_QC, posted by sigismund on March 30, 2012, at 14:22:17
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> Oh Vincent, that is just awful.
>Well awful cause I was on a pretty high dose of Seroquel (100mg) for my insomnia back in 2009 with no hangover side-effects the next day, so when my Doc suggest it to me again I say why not since I was able to tolerate that med in the past, a small 25 mg will not kill me... but my body seem very sensitive now to it and almost all the meds and always answer with cardiovasculars side-effects who worse my anxiety...
> I don't know anything about the pharmacology of trimipramine. I recall someone saying that it was a little like an AP. It doesn't feel to me as if it could cause anxiety or tachycardia but you are very sensitive.
>I think they use the Doxepin as an AP sometimes but the Trimiprimine is used mostly for depression... My Family Doc seem to not want to RX the low dose of Trimipramine saying it will just make my heart issues worse, well it was last january when I saw him the last time but I will ask him again about the Trimiprimine since at a low dose it's seem to be as safe as the Remeron and don't affect the noradrenaline like the Remeron do... I guess 2 mg will be enough for me.
> This is what I do. At least 2 hours before I want to go to sleep (for me this is 6pm) I take around 12.5mg trimipramiine or a little less. This way I have only a little hangover the next day. My guts are a bit sluggish, but that is about it.
>Ok... you go in bed early ;-) I normally go to the bed at 11 PM, so if I take it 2 hours before did I will fall asleep on the couch while I watch the tv? lol It take forever now to fall asleep, go in bed at 11 PM and don't sleep before 2-3 AM and i'm awake most of the time 2-3 hours later and it's very hard to fall asleep again and need to take extra Klonopin or Xanax since I wake up all the times now after vivid dreams and nightmares, that last since 1 month now and have panic attack also every night with the sweating on the forehead like I have fever, it's really weird and annoying and I don't like it at all... I don't like the fact that I also need to take extra benzo meds at night cause i'm addicted to them and they do nothing to help my anxiety now, i'm on a high dose of Klonopin 8 mg day + Xanax 0.25 mg day (usually 0.125 mg as soon as i'm awake in the morning and sometimes in the middle of the night or when I have very bad anxiety when i'm alone at home) and sometimes add some valium up to 20 mg 1 hour before I go to sleep... not suppose to take the Xanax but start it again when the panic attack in the middle of the night start 1 month ago...but will run out of stock soon and my Fam Doc will not RX it again...so I have to find a fix to treat my insomnia and increasing the Remeron is not the solution, don't want that high noradrenaline level in my brains...
> It is better for me than doxepin, which did not deepen sleep in the same way. Neither did amitrip. Mirtazepine did but lasted all the next day. Same with cyproheptadine.
>My experience with Mirtazapine (Remeron) in the past was positive, I was on 45 mg before bedtime back in 2007 but I find out that the sedative effect didn't last so I had to increase from 15 mg to 30 mg and then hit 45 mg and at the end it was not doing anything to make me sleep... but it was not also doing me anxious or more awake cause of the noradrenaline effect... but at the time I was addicted to coffee BIG time, for me 12 cups a day wasn't enough... lol It's when my stupid PDoc ask me to stop drinking coffee that things start to be worse for me!!! Weird no?
I was on Elavil for my headache back in 2007, at the same time then the Mirtazapine, went from 25 mg who did nothing at all and increase to 50 mg before bedtime and it was doing nothing just putting more weight on me so I stop it after 6 months... My experience with the TCA's is not very possitive, it's seem that most of them increase my heart rate into a tachycardia at rest state, especially the Nortriptiline... The Clomipramine wasnt also a good experience, had electric shock all over my body and had the worse headache ever on it...same for the Imipramine, don't know if i'm having a weak heart or something else, even if I have almost all the cardio tests done for my heart and nothing seem to be bad with it... I just don't know why I was so overreactive with those meds at the time...I was sensitive to them back in 2009 before I had the heart issues and anxiety who is mainly focused on my heart now, so I can't imagine returning on a TCA right now, that's why I wanted to know about the Trimipramine, it's seem to be the only one who don't affect the reputake of the NE, so maybe I will not have the scary fast heart rate on it...
> I take it with maybe 2mg prazosin split into two doses.
>
> This is physically calming.
>Have to ask about the Clonidine or Prazosin to my Doc also, the Inderal is not very good for the kind of problem I have right now, also it's not decreasing my heart rate like in the past, i'm on 5 mg x 3 times a day but overall only use 10 mg maximum a day cause if I use more my blood pressure drop too much and have worse anxiety... with the not stable blood pressure, orthostatic hypotension, low blood pressure OR high blood pressure, I don't know what is the problem but the inderal is not the med I need to treat my heart issues for sure... I don't know what make me so anxious, what is my problem, is it too much adrenaline or NE, is it too low adrenaline or NE, is it too low cortisol level, too low serotonin or too high...had tests done for the level of those neuro and results was very low for cortisol, adrenaline, low-normal NE and normal dopamine... normal VMA also... anyway...
Thanks for your answer, very helpful ;-)
poster:Vincent_QC
thread:1014003
URL: http://www.dr-bob.org/babble/20120328/msgs/1014569.html