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Re: Atypical Depression

Posted by kagome on March 20, 2012, at 22:18:32

In reply to Re: Atypical Depression » kagome, posted by SLS on March 19, 2012, at 7:18:01

> Are you sure? I didn't think naltrexone interacted directly with dopamine receptors at all. I could be wrong.

Well, supposedly naltrexone works by messing with the dopaminergic mesolimbic pathway, which includes dopmine and opiod receptors.

> Why do you think that buprenorphine would poop-out (tachyphylaxis)? I think my doctor would agree with you, but I am not so sure.
Cause it's an opioid, so one would develop tolerance and it would no longer work in the same way. Especially for an ex-opioid addict like I am (I believe I became addicted to pain relievers as a self medication technique that ended up making everything worse - this was ten years ago, btw, when I was 18, so I've been "clean" for some time)

> Marplan?
Never heard of it, but definitely sounds interesting. Do you know anyone who's tried it? Or what the side effect profile is like? I'm not happy about the weight gain part they mention but I suppose I should have better priorities. I'm so impressed with the amount of info you have!
Thanks so much,
kagome



This is the Hour of Lead-
Remembered, if outlived,
As freezing persons recollect the Snow-
First Chill, then Stupor - then the Letting Go.
--Emily Dickenson


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