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Re: Adding Parnate and prazosin.

Posted by papillon2 on February 24, 2012, at 7:28:26

In reply to Re: Adding Parnate and prazosin. » papillon2, posted by SLS on February 24, 2012, at 5:04:42

> What attracts you to prazosin? What is it about your particular case profile and case history that leads you to believe that prazosin is worth trying?

I have bad nightmares and a history of childhood trauma. Also our med combo is kinda similar and from what you've said, it appears to be helping you tremendously. Though come to think of it you've added Parnate as well.

I suspect my psychiatrist is going to want to change a med or two in a couple of months.

> What drugs are you currently taking?

Nortriptyline 100mg
Lamictal 200mg
Lithium 125mg
Melatonin 3mg
Aspirin 100mg for TCA-induced heart issues
The usual supplements

As an aside, I recently was prescribed a muscular skeletal relaxant called Norflex for short-term treatment of a neck injury. I'm interested in seeing what, if any, effect it has on my depression. Wouldn't mind some "mild euphoria".

> I would advise starting prazosin at a dosage of no more than 3 mg/day. I take it 3 times a day because it has such a short half-life, although twice a day should work, too. You could begin treatment with 1 mg at night. 3 mg/day was almost enough for me to glean a stable antidepressant effect from. It was obvious that I would lose the effect at the end of a dosing period, so I increased the dosage to 6 mg/day. This is still a low dosage. People go up to 20 mg/day to treat hypertension. Even 40 mg is considered safe.

Ah, so we're dealing with a different doseage regime. That should make quite a difference in terms of side effects.

Thanks Scott.


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