Posted by phidippus on February 8, 2012, at 16:26:06
In reply to prozac/abilify, posted by n_shrimpie on February 3, 2012, at 0:00:54
>i had no response except numbness and apathy, so i >quit after 4 weeks
it takes 6 to 8 weeks for the drug to actually start working.
>1 week of 2.5mg and a week of 5 mg so far, and >it's not doing anything except giving me insomnia
its supposed to boost your antidepressant, which may be too low. Insomnia is a side effect of Abilify.
<so maybe the anhedonia is not dopamine related?
Anhedonia is a complex matter. If dopamine were related it would have the effect of reducing anhedonia, because dopamine effects reward centers of the brain. Abilify is a dopamine antagonist which means it suppresses dopamine. Prozac agonizes dopamine, therby increasing it.
>i've had moderate-severe anhedonia all my life >since
You should try amitryptaline or chlomipramine. TCAs have a good track record with treating anehedonia.
Get off the Abilify and the Prozac and try a TCA.
Eric
poster:phidippus
thread:1009125
URL: http://www.dr-bob.org/babble/20120202/msgs/1009711.html