Posted by g_g_g_unit on February 6, 2012, at 3:35:29
In reply to Re: starting Parnate tomorrow » g_g_g_unit, posted by SLS on February 5, 2012, at 6:35:18
> > The low-dose (25-100 mg) Seroquel is a valid alternative for treating insomnia. There is even a chance that it will make the Parnate work better. The major metabolite of Seroquel (norquetiapine) inhibits the reuptake of norepinephrine (NE). I haven't investigated this well enough to know what dosages of Seroquel are necessary for this mechanism to have the best clinical effect. However, I have seen the addition of Seroquel produce a dramatic antidepressant effect in a young woman at 50 mg. She was taking Risperdal at the time.Strange. I replied to you last night, but it doesn't seem to have gone through. I noted that Seroquel, unfortunately, causes intolerable RLS in me, which makes it counter-productive as a sleep aid. I also experience a hangover effect.
>
> DO NOT give up on Parnate just because insomnia becomes a problem. You might have to treat the insomnia with the save aggressiveness with which you are treating the depression.Yes, the insomnia is what I'm dreading the most, to be honest. Loss of sleep - and the effects it has on cognition - kinda negates any benefits the drug might otherwise have, IMO.
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> Trazodone is a yucky drug. It almost always produces a hangover effect the next day. It does work, though.
>
> Can you list the specific drugs you have tried to treat insomnia and what were the results?
>I've tried the "Z-drugs" like Ambien etc., which allowed me to sleep rather restfully, but produced hallucinations.
I've tried Seroquel, which caused RLS.
I've tried Xanax, Temazepam, Lorazepam - none of which allowed me to sleep restfully, with all producing rebound depression (agitation, suicidal ideation) the next day.
poster:g_g_g_unit
thread:1009314
URL: http://www.dr-bob.org/babble/20120202/msgs/1009431.html