Posted by SLS on December 26, 2011, at 11:19:48
In reply to Re: lithium 5-ht1b + gsk-3b, posted by Phillipa on December 26, 2011, at 9:44:20
> How does lithium control and provide relief from mania?
One mechanism proposed is the inhibition of protein kinase C (PKC) and a reduction in the activity of membrane-bound G-protein dopamine and glutamate receptors. Another involves the inhibition of dopamine receptor glycogen synthase kinase-3 (GSK-3) signalling. Note that these explain mania rather than depression.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1005569
URL: http://www.dr-bob.org/babble/20111226/msgs/1005589.html