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Re: Should I go back up on wellbutrin sr (bupropion) » Zyprexa

Posted by SLS on November 10, 2011, at 6:34:15

In reply to Re: Should I go back up on wellbutrin sr (bupropion) » SLS, posted by Zyprexa on November 10, 2011, at 0:28:25

> Doc figured out it was making me anxious. Which the zyprexa was counteracting. So she first reduced the perphenazine and the wellbutrin. The perphenazine reduction didn't work, so she put me back up on perphenazine and asked if I needed to go back up on wellbutrin as well. I said now when I found out she was also reducing the zyprexa. The zyprexa reduction worked out so she reduced it more. All the time I was feeling like I still needed the wellbutrin, but she was not convinced it wouldn't raise anxiety and then I would need to go back up on the zyprexa again.


Have you had any experience with tricyclic antidepressants?

I bet you would have responded to nomifensine had it still been available. It was a potent inhibitor of both dopamine and norepinephrine reuptake. I am not a big believer that dopamine reuptake inhibition contributes to the antidepressant properties of Wellbutrin, although it is probably pro-noradrenergic. I am sure Sheldon Preskorn would disagree with me.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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