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Re: Dosyleptin How Come In Europe + Not USA? » jono_in_adelaide

Posted by ed_uk2010 on November 8, 2011, at 11:19:58

In reply to Re: Dosyleptin How Come In Europe + Not USA?, posted by jono_in_adelaide on October 30, 2011, at 18:31:06

> do you mean dosulepin/dothiapin phillips?
>
> That is the most widely used tricyclic in England, Europe and Australia...... its similar to nortriptyline, in that it is about equal to amitriptyline in antidepressant effects, but with far fewer side effects. Brand name is Prothiaden.

The name was changed from dothiepin to dosulepin when the 'th' sound was removed from drug names. Most languages (except English) do not have the 'th' sound, making dothiepin unpronounceable.

Dosulepin is still sometimes prescribed in the UK by GPs, but not usually to new patients. It is extremely toxic in overdose, and is not generally used by psychiatrists. Amitriptyline (rather than dosulepin) is used a lot here for chronic pain.

 

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