Posted by SLS on October 29, 2011, at 7:24:33
In reply to Re: doing better (clonazepam) » SLS, posted by linkadge on October 29, 2011, at 7:12:27
> >I hope you continue to have success with >clonazepam. Does the increased time sleeping >help with depression?
>
> Thats an interesting question. I feel more stable and certainly less burned out. I think the clonazepam lowers my mood a bit, mut still better than the insomnia.
>
> Linkadge
>
There are two possibilities that I can think of why you might feel somewhat "off". Clonazepam can make people feel more depressed or flatten affect (perhaps by reducing serotonin release), but these things are usually not severe. The other possibility is that you experienced a sort of circadian phase delay, which is known to cause depression to worsen temporarily. (This is the antithesis of sleep deprivation, where the circadian clock is advanced). Since your flattened affect has lasted beyond 5 days, I would guess that the clonazepam is to blame. Perhaps adding a low dose of lithium would help counteract the anti-serotonergic effects of clonazepam.http://www.ncbi.nlm.nih.gov/pubmed/2418653
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poster:SLS
thread:1001065
URL: http://www.dr-bob.org/babble/20111027/msgs/1001096.html