Posted by dgramovska on October 14, 2011, at 16:30:36
In reply to Re: 5HT2C antagonism, Agomelatine, Antipsychotics, posted by linkadge on October 14, 2011, at 15:50:11
Interesting, this cyproheptadine. So a quick scan on wikipedia says nothing about its potential as an antidepressant. But mustn't it have such potential, given its 5HT2C antagonist properties?
Also, I'd like to condense my original post. What I'm most interested in is whether 5HT2C antagonism has any likelihood of producing a manic reaction. It seems that with its and norepinephrine dopamine-releasing in the prefrontal cortex, it should be possible for it to induce mania.
That said, antipsychotics have 5HT2C antagonist properties, but we know they don't cause mania...
poster:dgramovska
thread:999547
URL: http://www.dr-bob.org/babble/20111006/msgs/999716.html