Posted by Dinah on September 29, 2011, at 11:01:58
In reply to Off-Label Antipsychotics May Not Be Safe, posted by Phillipa on September 28, 2011, at 20:04:11
>> In combined analysis of trials evaluating GAD, a "favorable response" was defined as showing at least 50% improvement on the Hamilton Anxiety "Rating Scale. Overall results showed that quetiapine was associated with a 26% greater likelihood of a favorable response at 8 weeks than placebo.
Augmentation with risperidone after not responding to other treatments was associated with a 3.9-fold greater likelihood than placebo of a favorable response (showing at least a 25% improvement on the Yale-Brown Obsessive Compulsive Scale) for patients with OCD." <<
They aren't going to lead with this, for sure. Admitting that Risperidone helps those who have not been helped by other treatments? Who's funding/running this story?
Also, there is no attempt at all to segregate the sort of patients who are most likely to respond well to AP treatment.
Drug companies aren't the only ones with an agenda.
It makes me furious that they do these studies on a group as wide as depression, or anxiety, or whatever, without dividing people up at all by type. It's like saying that casts are only helpful to ten percent of those with leg injuries, when the other ninety percent of injuries may not involve a broken leg.
To the people it's helpful with, it's very helpful. It can be a lifesaver, or at least make life worth living.
poster:Dinah
thread:998187
URL: http://www.dr-bob.org/babble/20110925/msgs/998238.html