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Re: WARNING: RASH, PSYCHOSIS, and other nasty effects » Jeroen

Posted by SLS on September 21, 2011, at 9:11:53

In reply to Re: WARNING: RASH, PSYCHOSIS, and other nasty effects, posted by Jeroen on September 21, 2011, at 8:48:38

> i was only taking lamictal and nothing else

Had you discontinued any antipsychotics just before beginning Lamictal?

At what dosage of Lamictal did you first encounter these side effects?

Lamictal does increase dopaminergic neurotransmission in the nucleus accumbens via glutamatergic disinhibition. Perhaps this is the etiology of your psychosis. The nucleus accumbens is enlarged in schizophrenia. However, I don't know how this might relate to you and the actions of Lamictal.

It was not my intention to invalidate your descriptions and conclusions. I was making the point that if these things do happen, they are a rare occurrence.

Have you tried Navane yet? Are you still taking Abilify? Perhaps you can perform a swap between these two drugs and add Seroquel. A friend of mine did exactly this, and is thinking and feeling the best that she can remember. I'm sure you know that I have a pet hypothesis that, for some people, Abilify can antagonize the therapeutic activity of other antipsychotics.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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