Posted by SLS on September 14, 2011, at 19:04:16
In reply to Fair trial of Pristiq 100 mg?, posted by jerseygal1 on September 14, 2011, at 18:09:06
> I was put on Pristiq 50 mg. back in May. It didn't do anything for me so the doc added zyprexa starting at 2.5 mg. increasing to 10 mg. That didn't work either so he upped the Pristiq to 100 mg. I've been at this dose for about 17 days and still no response. Is 17 days a long enough trial to see if there will be a response?
Not quite. I don't think it is worth the gamble to abort a trial of Pristiq at this juncture. If you can give it another week, you might see something. If not, then that would be the point at which you move on to other things. Some people who fail to respond to Effexor (the parent compound of Pristiq), will go on to respond to Cymbalta. I know someone who experienced poop-out with Effexor, but is doing marvelously with Pristiq.
> Or does this mean I'll have to go the route of a tricyclic or MAOI?
Pills from hell? They are not so bad. I prefer the side effect profile of nortriptyline to those of SSRIs.
Perhaps you can give Viibryd (vilazodone) a try before moving on to TCA or MAOI. It's an interesting drug with a clinical profile different from SSRIs, even though they both share the property of serotonin reuptake inhibition. Viibryd adds serotonin 5-HT1a receptor partial agonism (stimulation); a property that is unique among antidepressants.
Good luck with whatever you choose to do.
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.
poster:SLS
thread:996774
URL: http://www.dr-bob.org/babble/20110914/msgs/996780.html