Posted by poser938 on September 8, 2011, at 21:01:49
In reply to Re: Question about Low Dose Amisulpride, posted by bleauberry on September 8, 2011, at 19:14:47
well, the one med that used to help alot was cyproheptadine, i believe to its 5ht2c antagonism. i know that when you block this receptor it takes the brakes off dopamine release. but it's much different than something like ritalin. i never felt stimulated by it, it just worked to make me normal, which was great. to a certain extent it cured my adderall induced anhedonia in the past after about a month. but this time with ritalin it is beiing MUCH more difficult. i actuallly took cyproheptadine for 8 months, and had to raise my dose every couple of days because i would becoome tolerant fast. i got to a much too high dose and had to stop, and 8 months later my tolerance to it has still not gone away even though i most of the effects of it have gone away day by day. oh and i believe 5ht2c antagonism also increases norepinephrine release. i dont know what you're experiencing exactly, but maybe 5ht2c antagonism would be good for you if you havent tried it already.
more recently i tried buspar after reading about its beneficial effects on dopamine due to 5ht1a agonism, but it made me much worse after a single dose. so it seems 5ht1a agonism can either have a beneficial effect on libido for some people OR it could be bad for others. i've tried to read into why this might be,and cant come with anything. i know the reason is genetics, but you wouldnt happen to have any info in this would you? like maybe buspar stimulates presynaptic receptors in some and postsynaptic receptors in others? or it could maybe just be explained that it's simply effects people different because of genetics.
i'm trying to have a bacu-up plan in case amisulpride doesnt agree with me... so do you happen if Viibryds 5ht1a agonism may be a bit different?
poster:poser938
thread:996001
URL: http://www.dr-bob.org/babble/20110902/msgs/996205.html