Posted by SLS on July 20, 2011, at 6:24:44
In reply to Re: Study: AD use linked to **MORE** relapses, posted by Christ_empowered on July 19, 2011, at 23:50:15
> I believe it.
What do you believe, exactly. What evidence do you have to believe it?
> I think doctors need to be more careful about selecting patients for whom antidepressants, possibly used indefinitely, would be appropriate.
Yes. but would you know this in advance? Unfortunately, the selection criteria that would be used in such a protocol doesn't exist, and is poorly represented by the DSM IV. Soon, clinical treatment will be chosen by a combination of behavioral presentations and biological markers. In fact, I don't doubt that a biological phenotype will predict treatment outcomes. In the meantime, without these tools, I don't know how one would differentiate clinical presentations as a guide to treatment choices.
> Many people could probably benefit from other forms of treatment--exercise, anticonvulsants, stimulants, benzos, etc.--that might not induce these brain changes.
It seems to me that the treatments you suggest are ineffective in MDD, especially the endogenous type, and most presentations of BD depression. How do you justify your suggestions?
Are you still utilizing safe pharmacological modalities yourself? Have you ever? I know through personal experience that, of the available psychotropics, I respond to a treatment regime that must include a combination of two antidepressants - MAOI and TCA.
Personally, I have little doubt that antidepressants can produce profound and perhaps permanent untoward effects in CNS function. However, this is not something that this article addresses with supportive scientific evidence. It is, like my opinion, a personal theory on the part of the author that is made without objectively acquired information. I have yet to read the full text being referred to as has been provided by Jane D., though.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.
poster:SLS
thread:991400
URL: http://www.dr-bob.org/babble/20110714/msgs/991453.html