Posted by Vasilis on June 13, 2011, at 17:56:55
In reply to Re: Prozac+Amitriptiline+Perphenazine Need to be sure, posted by Christ_empowered on June 13, 2011, at 17:33:03
> hey. Using a TCA antidepressant (the older ones, like amitrip) and an antipsychotic (perphenazine) in combo for psychotic depression used to be common. Then the SSRI drugs (such as Prozac) and the "atypical" antipsychotics" (such as zyprexa) came out and, in the US at least, its become more common to use the newer drugs (SSRI+atypical instead of your combo, TCA+old-school antipsychotic).
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> I don't understand why you're on 2 antidepressants. Is the idea to boost your energy levels? It strikes me as a kind of risky combo. What are your symptoms? I mean, I know you've been diagnosed with psychotic depression, but what's really bothering you--agitation, voices, insomnia...??
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> I'd personally try just one antidepressant and the perphenazine for a couple months and then if they psychosis is gone drop the perphenazine, or at least get the dose lower (in low doses it acts as a tranquilizer, not so much an antipsychotic agent).
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> Sorry you're going through a rough patch.I am on two antidepressants because here in Greece perphenazine is sold only as a combo Amitriptiline-perphenazine. The doctor is perfect but i am unsure of his knowledge of pharmakokinetics.
poster:Vasilis
thread:987960
URL: http://www.dr-bob.org/babble/20110610/msgs/987973.html