Posted by desolationrower on June 11, 2011, at 14:18:09
In reply to Re: what causes nardil weight gain, posted by SLS on June 11, 2011, at 4:40:04
> > Can nardil do something to cause weight gain other than eating more? I've put on 2 kilos in the last 2 weeks that i've been on it yet i'm not eating much at all, thyroid tests point more towards over active so it isn't that either.
>
> In my experience, weight gain is independent of, but exacerbated by, increased appetite. I believe Nardil affects glucose/insulin dynamics. Whatever it is, it is definitely a metabolic effect.
>
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> - Scotti'd guess there is almost certainly something with appetite, but a good chance of something else too.
i thought i posted something about this relatively recently, but i can't find it.
oh i found it. http://www.dr-bob.org/babble/20110321/msgs/981503.html just a bunch of jumbled thoughts though.
THere might be something about the lowered liver function, plus less activation of sympathetic nervous system, compared to parnate. Also, there is conflicting evidence, but parnate seems better at downregulating 5t2 receptors, though i'd guess phenelzine is better at activating them. that would affect appetite.
I kind of hate how there is so little evidence on the mechanisms of old drugs.
also keep in might short term weigh fluctuation can be related to salt/glucose and water.
-d/r
Better living through chemistry, socialism, and big phallic rockets (with a side of roquette)
poster:desolationrower
thread:987536
URL: http://www.dr-bob.org/babble/20110610/msgs/987758.html