Posted by sigismund on June 3, 2011, at 14:57:16
In reply to Agomelatine, posted by viper1431 on June 3, 2011, at 10:39:31
It worked very well with me to begin with.
My experience was that the melatonin agonism became less robust over time than the 5ht2c antagonism, or at least that was my explanation for the fact that my sleep got worse (after getting better) whereas the dopaminergic type push is still around. Whether the dopaminergic push (which lasts all day....it must be a downstream effect so the 2 hour half life is of limited relevance) is good for sleep I have my doubts about. I've taken it in various doses for a couple of years. It's been good for me, overall. Given the available alternatives, I mean. Ask away.
poster:sigismund
thread:987012
URL: http://www.dr-bob.org/babble/20110529/msgs/987025.html