Posted by desolationrower on May 5, 2011, at 22:49:50
In reply to Re: Need to figure out meds to take for OCD and SA » desolationrower, posted by Chris2011 on May 5, 2011, at 22:00:08
> > btw you can get inositol by the kilo; for the 18g/d dosage it can get expensive if you get it in small amounts..
> >
> > For the stomach issues, i'd try to break it into a couple doses with meals in between
> >
> > also, overlap with this thread going on right now too http://dr-bob.org/babble/20110418/msgs/984054.html (i am sort of getting them confused in my head, honestly)
> >
> > i do think phenelzine is superior for anxiety, although you could try the valproate! I think you both mentioned too much anxiety when first starting phenelzine. And my best guuess is excess 5ht2 activity, and take risperdal to fix.
> >
> > abilify is a somewhat unusual drug, even for atypical antipsychotics. It would probably be worth a trial of another ones, like risperidone or ziprasidone,
> >
> > -d/r
>
> Thanks for the response d/r. As far as possible excess 5ht2 activity, did you mean as an existing condition or as a result of taking phenylzine?Well my guess is overactive in general, and not responding well to phenelzine. Normally with an MAOI (i know it was shown for tranylcypromine, but i think phenelzine as well ) and half the time ssri activate 5ht2 so much that they downregulate 5h2 receptors over several weeks, and this might be part of why it takes a few weeks for it to really lift depression. If that isn't working well for you, doing it artificially by just blocking it might be better. I think its worth a try.
>Hard for me to think too clearly right now as I started 25mg of Anafranil this week and it is somewhat cognitively numbing. I do think you're on to something with the suggestion of risperdal or Abilify. I have generalized social anxiety, with most of the hallmark symptoms, but the most debilitating symptom is an almost irrepresible feeling of being criticized and judged by anyone within earshot of me when I speak, whether it's at work, or anywhere in public, despite the lack of any evidence. A feeling that almost everybody is observing me in public and waiting for me to screw up or act unconfident so they can do something to make me feel bad. Cognitive therapy has helped somewhat as far as reasoning through those thoughts/feelings, but I wonder if I'm dealing with paranoia or a paranoid flavor of social anxiety. Supposedly what separates psychosis from SA is that the person can't fully realize the irrationality of their beliefs, as is the case with me a lot of the time.This could be true, but i think it could be a false lead. Not many people with social anxiety respond well to the higher doses of antipsychotics that reduce DA function and lower positive symptoms for schizophrenics (and as well, those higher doses tend to make the negative symptoms worse. and neg symptoms have some commonality with social anxiety). Personally, i had some improvement on .25 mg risperdal, but felt much worse (lethargic, no emotion, just would lay on the ground not interesting in doing anything) on 1 mg (or 2 mg, i forget)
I'm reccomending them more because low doses primarily antagonize 5ht2, not for higher doses that block DA function (though this might help with OCD, so keep that in mind for dosages).
-d/r
Better living through chemistry, socialism, and big phallic rockets (with a side of roquette)
poster:desolationrower
thread:983447
URL: http://www.dr-bob.org/babble/20110502/msgs/984685.html