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Re: Nothing Works

Posted by desolationrower on April 30, 2011, at 4:47:11

In reply to Re: Nothing Works » linkadge, posted by SLS on April 23, 2011, at 9:28:34


> I will be adding fish oil to my treatment regime. Can you describe what your experience with it was?
>
> Thanks.
>
> I have already added phosphatidylserine, a substance that is supposed to work with fish oil to help support neurotrophism.
>
>
> - Scott

Someone already mentioned taurine as well, which is also abundant in seafood. If possible, i would suggest eating fish as opposed/addition to fish oil, as it contains the w-3 oil, taurine, as well as other things. Of course, a fish oil pill is better than nothing, and high dose w-3 might be useful, at least to try. There is less evidence that i've seen for dose for mental health, but for other aspects the benefits taper off quickly after about .5g/day of EPA/DHA (which is still more than the standard american diet provides), and i think for most people some fish, and avoiding 'vegetable oil' is enough for proper metabolism re:polyunsaturated fats & their metabolites. THere might be interesting interactions with COX inhibitors (aspirin/ibuprofen) which are beneficial for mental health - cox turns long-chain w-3 and w-6 fatty acids into signaling molecules. So it might either antagonise or synergise with high dose fish oil, which may or may not be better than the normal amount. some stuff to think about or try, i guess. w-3s have effects beyond just the eicoisinoids. (for both scott and cyban, actually)

for the OP, that is a long list of things to take, some stuff looks like its working at odds. And i agree about diet etc, perhaps yours it good, but are you generally in good health and is there anything that changed when you changed to bp again? also, i would recommend (actually, i'd rec it for everyone) to go to http://cronometer.com/ and put in your usual meals and see if you are getting enough of everything. CSA veggies are great, but there still could be something missing or that you are out on the far edge of the bell curve as far as how much you need. All kinds of crazy genetic weirdnesses are possible.

MAOI: I would suggest phenelzine aka nardil as the much better choice for someone with prominent mania, agitation, etc.

N acetyl cysteine or riluzole both work on glutamate, and have *some but not great evidence they might help with substance use and mood disorders.

How is your sleep? have you had a sleep test? I would suggest some melatonin, maybe some sleep drugs too. your symptoms sounds like how i feel when i don't sleep...

-d/r


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poster:desolationrower thread:983569
URL: http://www.dr-bob.org/babble/20110418/msgs/984143.html