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Re: The nature of dopaminergic meds? » floatingbridge

Posted by Bob on April 13, 2011, at 16:53:12

In reply to Re: The nature of dopaminergic meds? » floatingbridge, posted by floatingbridge on April 13, 2011, at 6:34:30

> What are your thoughts on maoi's and dopamine agonists in your own situation?
>
> Thanks,
>
> fb


FB,

I am very frustrated with the dopamine modifying meds as I am with a few other treatments. These meds in particular provide a robust immediate response which maddeningly fades away all too quickly giving me an ephemeral glimpse of health. This short duration response is probably the closest I've come in a long time to feeling normal but only lasts a day or two.

It seems to me sometimes like dopamine is one of the keys to a successful treatment, but it needs to be modified only in certain areas of the brain - something we don't know how to do. One of my main problems has always been that my brain seems to adapt to whatever treatment it gets and then the therapeutic effect fades. This adaptation also seems to get faster and faster as time goes on and exposure to treatments increases producing what could now be called a "tardive dysphoria" and a truly treatment-resistant patient.

Bob

 

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