Posted by linkadge on March 22, 2011, at 16:15:21
In reply to Re: Does Wellbutrin work anything like Nortriptyline?, posted by mtdewcmu on March 22, 2011, at 15:24:03
Nortriptyline probably results in a higher NE reuptake inhibiton at clincal doses. I remember a study showing that even at 450mg, wellbutrin only results in a low (10-15%) occupancy of the norepinephrine / dopamine transporters.
That doesn't mean that nortriptyline is more stimulating since, as mentioned, it has antihistamine / antiserotonin effects.
Linkadge
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thread:980889
URL: http://www.dr-bob.org/babble/20110321/msgs/980908.html