Posted by jedi on March 21, 2011, at 0:59:33
In reply to Re: Tri + nardil = no hypertensive (Correction), posted by Michael Bell on March 10, 2011, at 12:20:30
> I meant to say amitryptiline instead of nortryptiline.
Hi,
I have used nortriptyline with Nardil and had no problem with the combination. Nortriptyline is the major metabolite of amitriptyline and works in a similar fashion to raise norepinephrine levels but has less side effects, in my opinion. I studied the combination extensively before taking them together. I started the tricyclic first and added the Nardil to it. I believe that is the safest way to combine the medications, alternatively they can be started simultaneously. I think the reason the two meds can be combined safely is that the nortriptyline has very little affect on serotonin. Tricyclics that have more of a serotonin affect would be much more dangerous to combine with a MAOI (serotonin syndrome). I have also read that the norepinephrine in the tricyclic can help eliminate the problem with tyramine containing foods. I didn't test that theory so don't know how true it is.
Jedi
http://www.dr-bob.org/babble/20050811/msgs/540971.htmlhttp://www.ncbi.nlm.nih.gov/pubmed?term=PMID%3A%207560546
Jedi
Treatment resistant, atypical, double depression with social anxiety.
Nardil + clonazepam
poster:jedi
thread:980343
URL: http://www.dr-bob.org/babble/20110220/msgs/980835.html