Posted by ed_uk2010 on March 3, 2011, at 15:30:07
In reply to Because I gained weight on Nort. does that mean al » ed_uk2010, posted by Laney on March 1, 2011, at 15:10:36
>Why is it that desiprimine doesn't? How is desiprimine on depression compared to Nort? I'm currently tapering the Nort. and am on 20mg. paxil.
>
> What other side effects would be likely with Desip?Desipramine is pretty selective as an NE reuptake inhibitor. It lacks the sedative and antihistamine effects of most TCAs.
Desipramine causes noradrenergic-type side effects very frequently eg. dry mouth, increased heart rate, sweating and constipation.
It is not more effective for depression than nortriptyline, but probably not less effective either. It suits some people better. Nortriptyline might be more suitable for those with insomnia.
poster:ed_uk2010
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