Posted by jedi on February 13, 2011, at 0:19:15
In reply to Re: Nardil side effects still a problem, posted by Sailboat77 on February 12, 2011, at 16:56:28
Hi Sailboat,
I have had a couple of trials with Parnate. Unfortunately, on the last trial, I had a rare spontaneous hypertensive episode which kept me from giving it the fair trial it deserved. I liked Parnate because it is much less likely than Nardil to cause weight gain and has less sexual side effects. I don't believe it is as good for social anxiety as Nardil. Nardil seems to be more of a relaxing medication, after an initial chance of hypomania; while Parnate seems to be more activating.I have and still do take Seroquel occasionally for insomnia. Among its many other pharmacological actions it is a potent H1 receptor antagonist. At low dosages, of less than 25mg, that is one of it's primary functions. In other words, it is an antihistamine, similar to diphenhydramine hydrochloride(Benadryl). I have found doses as low as 12.5mg to be affective for my insomnia. In the initial stages, I found insomnia on Parnate to be worse than Nardil. You may need the 50mg now and be able to reduce it later on. Dosages of quitiapine for bipolar disorder and schizophrenia range from 200 to 800mg and affect many other receptors. Watch out for rebound insomnia after taking Seroquel long term.
Thanks for the information on orthostatic hypotension. I know this is a very serious problem for many using MAOIs. Some people can't even continue their trials because of this side effect.
Wishing you the Best,
Jedi
> I've taken Nardil before but right now I currently take 60mg of Parnate (a different MAOI with similar side effects). I've experience almost of all the negative symptoms you have to one degree or another. After 6 weeks now, my doctors and I have found some remedies to counter the persistent issues.
>
> (Insomnia): 50mg of Seroquel is the only thing that seems to work for me. Ambien and Lunesta were largely inefficient and helped very little. I also take Xanax on occasion to slow down racing thoughts.
>
> (Orthostatic Hypotension): This has been a HUGE issue for me. I would stand up and fall over or get extremely dizzy within minutes due to falling blood pressure. You can take either Florine or Midodrine to alleviate symptoms. The Florinef gave me insomnia so I recommend Midodrine instead.
>
> I hope my own experience helps some- I know the side effects can be difficult to endure.
Jedi
Treatment resistant, atypical, double depression with social anxiety.
Nardil + clonazepam
poster:jedi
thread:979083
URL: http://www.dr-bob.org/babble/20110130/msgs/979178.html