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Re: Pramipexole and sleep

Posted by Conundrum on February 11, 2011, at 17:36:18

In reply to Pramipexole and sleep, posted by diego on February 11, 2011, at 15:38:25

> 50 yo male, been taking testosterone for depression for years. No other meds except the occasional 0.5 mg Xanax for sleep.
>
> On a lark I picked up some pramipexole 0.5 mg and have been taking one a day for about a week. Hasn't helped with the mild anhedonia -- which is probably nothing more than the result of a particularly grey winter, BUT I haven't slept better in ages!
>
> The stuff has no effects or side-effects that I can tell, so maybe the sleep is just coincidence, but I doubt it.
>
> Any anecdotal evidence to support my theory?
>
> Thanks.

Sure, there is a lot of evidence that it makes one tired. Its actually the time the drug starts to wear off that it makes one tired. If you look at sites like askapatient.com and read reviews for that drug you will hear people complaining about how it makes them very tired. It has an 8-12 hour half so that is probably what causes this, when the drug wears off later in the day. I wonder what day and evening dosing would do? Cause DA receptor downregulation or just cause insomnia, or both?


Complaints: post-SSRI problems: anhedonia, memory and concentration problems, sexual anhedonia. )
Country:USA
Currently taking 2.5 mg prozac, Multi B vitamin

 

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