Posted by medamorphosis on February 9, 2011, at 21:22:04
In reply to Norepinephrine, posted by greenwillow on January 15, 2011, at 1:38:50
Well for me, NE gives focus, motivation, concentration and stamina. Actually good for certain anxieties/depressions which often make the mind go blank. Seems to enhance cognitive abilities, especially in social anxiety. Tho it certainly dont exactly get rid of typical fears. But it should get you outa bed!
NRI: Reboxetine- little, if any mood lift but motivation, focus and stamina increase.
TCA NRI: Lofepramine (or desipramine, it's main metabolite)- mild yet persistant mood lift, motivation, stamina, focus and great with a benzo!
DNRI: Bupropion- mild mood lift of a different kind, more like a low dose amphetamine tho didn't last long enough. Still the motivation, focus and stamina increase, but pooped out too quickly.Others which increase NE as 'PART' of thier action are MAOIs, SNRIs and most TCAs. More probably.
Definitely best when part of a multi-action med or mixed action combo. And IMO forget venlafaxine! Just another SSRI in my book. And think twice before trying mirtazepine too- the NE effects only appear at higher than norm doses (low to norm doses usually make you 'zombified'). And very few docs like to prescribe high doses (45mg+), and even with a high dose theres no gaurantee of the fog dissappearing.
Tho velafaxine + mirtazepine is described by some pdocs as 'Rocket Fuel'! What causes this strong NE effect from the combo i do not know.Med
U.K.resedent
Ills: Avoidant Personality Disorder, major depression, addictive personality, alcoholism
Regime: 100mg isocarboxazid, 4mg clonazepam, 50mg agomelatine, high-dose vits & mins
poster:medamorphosis
thread:976826
URL: http://www.dr-bob.org/babble/20110130/msgs/979021.html