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Lexapro Zoloft Combination

Posted by Malco47 on February 4, 2011, at 3:21:37

Hello friends,

I have been begun taking a combination of two SSRI's. I am taking 15mg Lexapro and 50mg Zoloft. I had been taking 25mg Lexapro alone. My psychiatrist explained that lower doses of two SSRI's is basically equivalent to a higher dose of one SSRI.

Since it is assumed that 10mg of Lexapro is similar in effect to 50mg of Zoloft, we made the change accordingly.

He suggested the change because Zoloft is more "activating" than Lexapro, and therefore the combination would cause less drowsiness than Lexapro alone, while still maintaining the same basic anti-anxiety and anti-depressant effects.

I am wondering, has anyone else used this strategy? It makes sense if he is correct that the combination of two smaller SSRI doses has no more risk or side effects than taking a higher dose of either one alone. Would anyone like to share their experiences? Thank You!


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poster:Malco47 thread:978635
URL: http://www.dr-bob.org/babble/20110130/msgs/978635.html