Posted by Conundrum on February 1, 2011, at 20:28:28
In reply to Re: How long before I give up on Nortriptyline?, posted by Laney on January 30, 2011, at 14:56:08
> Yes, approx. two weeks at 75mg. But like I said it seemed to work much quicker when I first started it. Thanks! Yes, I will get levels tested.
>
> P.S. Are tricyclics reuptake inhibitors?
>
> Thanks!
>
> LaneyWith the exception of Tianeptine, almost all of the tricyclic antidepressants are reuptake inhibitors. Nortriptyline blocks the reuptake of norepinephrine fairly strongly and the reuptake of serotonin moderately. They do a lot of other things as well, but the reuptake type of mechanisms seem to take awhile to work. Blocking of postsynaptic receptors seems to work a lot faster like histamine making you tired and D2 blockade with antipsychotics works fairly quickly.
Complaints: post-SSRI problems: anhedonia, memory and concentration problems, sexual anhedonia. )
Country:USA
Currently taking 2.5 mg prozac, Multi B vitamin
poster:Conundrum
thread:978280
URL: http://www.dr-bob.org/babble/20110130/msgs/978504.html