Posted by Conundrum on January 22, 2011, at 14:08:12
In reply to New antidepressant just approved. Vilazodone (nm), posted by roscopeeco on January 22, 2011, at 2:07:52
> ,
Pharmacologically, it looks unimpressive. Why would you want 5 HT1A partial agonism if you have serotonin acting as a full agonist. Isn't that the way serotonerigic drugs are though to work, by activating and downregulating that receptor? The only advantage I can see, from a pharmacological standpoint, is that the partial agonist might work more like an antagonist, and keep serotonin output higher than on a normal SSRI.
Complaints: post-SSRI problems: anhedonia, memory and concentration problems, sexual anhedonia. )
Country:USA
Currently taking 2.5 mg prozac, Multi B vitamin
poster:Conundrum
thread:977653
URL: http://www.dr-bob.org/babble/20110115/msgs/977685.html