Posted by SLS on January 19, 2011, at 11:38:19
In reply to Prozac isn't kicking in..., posted by Conundrum on January 19, 2011, at 10:25:30
Hi.
> Also my pdoc wants me to go to the treatment resistant depression clinic at UPenn in Philadelphia.
Can you describe more about their program? I'd be willing to make the trip.
Is Jay Amsterdam still around?
Anything you share would be greatly appreciated.
Thanks.
You might consider adding low dosages of lithium 300 - 600mg. For adding an "antipsychotic" with antidepressant properties, Abilify would be my first choice. Zyprexa might work, but the magnitude of weight-gain and risk of diabetes would not make it an ideal choice. Some people have luck with Geodon, but not as many. Geodon is truly the only second-generation antipsychotic (atypical) that is weight-neutral. Abilify isn't too bad as far as weight gain is concerned, but it can sneak up on you if you don't step on the scale every now and then.
Which other antidepressants have you tried? Did any of them tickle the brain?
Wellbutrin is known to be helpful when added to Zoloft. However, I have not heard that it is particularly potent in combination with Prozac.
A trial of lithium or Abilify can yield results in as little as one week. Therefore, if you don't see an improvement by 2 weeks of a therapeutic dosage, you can judge the drug to be ineffective.
Keep an eye on a new drug called lurasidone.
"Lurasidone (SM-13,496) is an atypical antipsychotic developed by Dainippon Sumitomo Pharma.[1] It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010, under the brand name Latuda[2] and is currently pending approval for the treatment of bipolar disorder in the United States." - Wikipedia
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.
poster:SLS
thread:977419
URL: http://www.dr-bob.org/babble/20110115/msgs/977427.html